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人工知能・臨床研究・医療イノベーション

Large Language Models in Patient Education and Clinical Communication: Reliability, Safety, and Oversight

著者

  • Li Yang 著者

キーワード:

clinical language models; artificial intelligence; patient safety; health equity; implementation; clinical evaluation

要旨

Background: The adoption of clinical language models in patient education, discharge instructions, and clinical correspondence creates opportunities to improve clinical services, but technical performance alone does not establish patient benefit. Objective: To critically examine applications, evidence, safety, equity, and implementation of clinical language models. Approach: This narrative review develops an analytical synthesis of established clinical AI principles and reporting guidance; it does not report a systematic search, a new dataset, or an empirical trial. Findings: Key opportunities include plain-language explanation, multilingual support, and document summarization. Important limitations include hallucination, outdated evidence, and misleading fluency, as well as unsafe advice, omission of warnings, and disclosure of sensitive data. Responsible adoption requires source attribution, escalation pathways, and mandatory human approval, transparent reporting, and evaluation of factual accuracy, readability, actionability, comprehension, and harm. Conclusion: The clinical value of clinical language models depends on fit with the care pathway, prospective evaluation, accountable human oversight, and sustained monitoring after deployment.

参考文献

Ayers, J. W., Poliak, A., Dredze, M., Leas, E. C., Zhu, Z., Kelley, J. B., Faix, D. J., Goodman, A. M., Longhurst, C. A., Hogarth, M., & Smith, D. M. (2023). Comparing physician and artificial intelligence chatbot responses to patient questions posted to a public social media forum. JAMA Internal Medicine, 183(6), 589–596. https://doi.org/10.1001/jamainternmed.2023.1838

Sallam, M. (2023). ChatGPT utility in healthcare education, research, and practice: Systematic review on the promising perspectives and valid concerns. Healthcare, 11(6), Article 887. https://doi.org/10.3390/healthcare11060887

Singhal, K., Azizi, S., Tu, T., Mahdavi, S. S., Wei, J., Chung, H. W., Scales, N., Tanwani, A., Cole-Lewis, H., Pfohl, S., Payne, P., Seneviratne, M., Gamble, P., Kelly, C., Babiker, A., Schärli, N., Chowdhery, A., Mansfield, P., Demner-Fushman, D., ... Natarajan, V. (2023). Large language models encode clinical knowledge. Nature, 620, 172–180. https://doi.org/10.1038/s41586-023-06291-2

World Health Organization. (2024). Ethics and governance of artificial intelligence for health: Guidance on large multi-modal models. https://www.who.int/publications/i/item/9789240084759

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発行日

2026-10-09

巻号

セクション

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